Doctor/Provider Profile

K. Mark Payne, M.D.

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  • Professor
  • Director, Gastrointestinal Endoscopy Service
  • Director, Division of Gastroenterology & Hepatology
  • Co-Medical Director, Digestive Disease Center Service Line
Degree M.D.
School M.D. awarded by University of Kansas, 1982
  • University of Kansas Medical Center
  • University of Kansas
Board Certification
  • Internal Medicine
  • Internal Medicine: Gastroenterology
  • Gastroenterology & Hepatology
Clinical Interests
  • Endoscopic retrograde cholangiopancreatography (ERCP)
  • Endoscopy
Accepts New Patients Yes
To request an appointment call our representatives at 843-792-1414


Ashley River Tower
25 Courtenay Drive
Charleston, SC 29425
Map & Directions


Dr. Payne is the Director of the Division of Gastroenterology and Hepatology at the Medical University of South Carolina.   He earned his M.D. at the University of Kansas, following which he completed an internship and residency in Internal Medicine and a Fellowship in Gastroenterology, also at the University of Kansas. He is board certified in internal medicine and gastroenterology.

Dr. Payne is a member of several organizations, including, the American Gastroenterological Association; American Society of Gastrointestinal Endoscopy; and American College of Gastroenterology.  He is also a member of MUSC’s Mission Based Management Committee, the Department of Medicine Compliance Committee, and the Conscious Sedation Committee. 

Dr. Payne’s clinical interests include advanced endoscopy, pancreatobiliary endoscopy, hepatology and clinical service management and administration.

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