Nicole Brooks Cain, M.D.

Accepting New Patients
Degree M.D.
School Marshall University Joan C. Edwards School of Medicine
  • Children's Hospital of Pittsburgh of UPMC
  • Children's Hospital of Pittsburgh at UPMC
Board Certification
  • Pediatrics
  • Pediatrics: Pediatric Cardiology
  • Pediatric Cardiology
Clinical Interests
  • Arrhythmias
  • Wolff-Parkinson-White syndrome
  • Electrophysiological testing
  • Syncope (fainting)
  • Congenital heart disease
Accepts New Patients Yes

New Patients

843-876-0444 843-876-0444

To request an appointment call our representatives at 843-792-1414

Returning Patients


MUSC Children's Health Pediatric Cardiology - Greenville
200 Patewood Drive
Greenville, SC 29615
Map & Directions
Children's Hospital
165 Ashley Avenue
Charleston, SC 29425
Map & Directions
Children's Health Specialty Care North Charleston
2750 Dantzler Drive, Unit 102
North Charleston, SC 29406
Map & Directions
Children's Health Specialty Care Mount Pleasant
2705 Highway 17, Suite 100
Mount Pleasant, SC 29466
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Dr. Nicole Cain graduated from Marshall University in 2001 and completed medical school at the Joan C. Edwards School of Medicine at Marshall University in 2005. She went on to complete both her pediatric residency and pediatric cardiology fellowship training at the Children's Hospital of Pittsburgh of UPMC. She pursued additional training in pediatric electrophysiology at the Medical University of South Carolina and joined the MUSC faculty as a pediatric electrophysiologist in 2011. Dr. Cain’s academic interests include cardiac arrhythmias such as supraventricular tachycardia (SVT) and Wolff-Parkinson-White Syndrome (WPW). As the director of pediatric electrophysiology, Dr. Cain performs electrophysiology studies and ablation procedures in patients from all over SC and implants pacemakers and defibrillators in teenage and adult patients. 

Dr. Cain’s research interests include arrhythmias in the single ventricle population and in patients with congenital heart disease. She is an active research participant in multi-center research studies involving arrhythmias and EKG screening in the Pediatric Heart Network (PHN) and in the Pediatric and Adult Congenital EP Society (PACES).