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The Digestive Disease Center

Established in 1995 by Peter Cotton, M.D., a pioneer in the field of endoscopy, MUSC’s Digestive Disease Center (DDC) brings together gastroenterologists, surgeons, and radiologists who have special expertise in treating digestive problems. Most patients are managed with medical, endoscopic, and nonoperative therapies, but when these treatments are ineffective, patients are referred for surgery. Advanced diagnostic and therapeutic endoscopy and management of esophageal diseases and general motility disorders, liver disease (and transplantation), complex pancreatic and biliary diseases, and gastrointestinal oncology are particular strengths of the DDC. These strengths are complemented by the recent recruitment of Kevin F. Staveley O’Carroll, M.D., PhD, to build a strong clinical program in liver, pancreas, and foregut tumors.


Program Highlights

Autologous Islet Cell Transplantation

Back from the Abyss

MUSC’s Digestive Disease Center, long a center of excellence in the treatment of pancreatic disease, has performed almost 90 pancreatectomies since 2009. Auto Islet Cell Transplantation helps prevent brittle diabetes in patients undergoing complete pancreatectomy.

Freezing Cancer Out: Cryotherapy for Upper GI Lesions

Freezing Cancer Out

Cryotherapy offers an alternative to patients with gastrointestinal (GI) tumors who do not respond to or cannot tolerate radiofrequency ablation (RFA).

New Hope for Patients with Medication-Refractory GERD


David B. Adams, M.D., began implanting the LINX® reflux management system in select patients shortly after its approval in 2012 by the FDA as a safe and effective treatment for medication-refractory gastroesophageal reflux disease (GERD).  


Faculty Leadership

David B. Adams, M.D., FACS

David B. Adams, M.D., FACS

David B. Adams, M.D., is Chief of the Division of Gastrointestinal and Laparoscopic Surgery and Co-Director of the Digestive Disease Center at the Medical University of South Carolina (MUSC).

K. Mark Payne, M.D.

K. Mark Payne, M.D.

K. Mark Payne, M.D., is the Director of the Division of Gastroenterology and Hepatology and a Professor of Medicine in the Department of Medicine at the Medical University of South Carolina (MUSC).